KPV

KPV Injectable (Research Use Only)
High-Purity Research Formula for Laboratory Applications

Product Description:
What is KPV?

The KPV peptide is a tripeptide composed of proline, lysine, and valine with anti-inflammatory and antimicrobial properties. Originally derived from the alpha-melanocyte-stimulating hormone (α-MSH), KPV has demonstrated several key functions, including reducing inflammation, enhancing wound healing, reducing inflammation in the digestive system, and improving skin conditions such as eczema and psoriasis (1).

UK Studies have found that the ability of the KPV peptide to modulate immune responses is extremely valuable not only for dermatological applications but also for managing inflammatory bowel conditions such as Crohn’s disease and colitis. Generally, KPV is administered topically, orally, or via injection, offering flexibility depending on the targeted use and intended outcome of the study.

UK Research continues to explore its therapeutic potential for broader inflammation-related disorders and immune regulation (2).

Molecular Formula: C16H3oN4O4

Amino Acid Sequence: Lys-Pro-Val

Molecular Weight: 342.43 g/mol

Potential Benefits of KPV

Research professionals investigating KPV have identified that the popular tripeptide could hold the following benefits:
- KPV may reduce inflammation, making it beneficial for treating inflammatory conditions.
- KPV enhances wound healing and accelerates tissue repair.
- May protect against bacterial infections.
- KPV may improve skin concerns like eczema and psoriasis.
- Helps manage inflammatory bowel diseases like Crohn’s disease and colitis by reducing inflammation in the gastrointestinal tract.

KPV FAQs

Can KPV have any adverse effects?

In general, people regard KPV as being safe and suited to their bodies, with hardly any side effects reported. It has a natural peptide formation and has been shown in research to be bioactive orally, subcutaneously, intravenously or topically. However, as with any drug, there’s a possibility that it may interact with other medicines.

If you are using KPV or any kind of peptide therapy, in those cases, it is advisable to seek the advice of a suitably qualified healthcare professional.

Is KPV approved for human consumption?

At the current time of writing, KPV has not been approved by the FDA for human consumption. It is currently categorized as a research peptide, and while it is available for purchase, it is typically labelled for in vitro research purposes only. The FDA has noted a lack of sufficient safety data regarding its efficacy in humans.

Scientific Research

(1) Pawar K, Kolli CS, Rangari VK, Babu RJ. Transdermal Iontophoretic Delivery of Lysine-Proline-Valine (KPV) Peptide Across Microporated Human Skin. J Pharm Sci. 2017 Jul;106(7):1814-1820.

(2) Xiao B, Xu Z, Viennois E, Zhang Y, Zhang Z, Zhang M, Han MK, Kang Y, Merlin D. Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis. Mol Ther. 2017 Jul 5;25(7):1628-1640.

(3) Bonfiglio V, Camillieri G, Avitabile T, Leggio GM, Drago F. Effects of the COOH-terminal tripeptide alpha-MSH(11-13) on corneal epithelial wound healing: role of nitric oxide. Exp Eye Res. 2006 Dec;83(6):1366-72.

(4) Duarte-Mata DI, Salinas-Carmona MC. Antimicrobial peptides´ immune modulation role in intracellular bacterial infection. Front Immunol. 2023 Mar 28;14:1119574. 

(5) Luger TA, Brzoska T. alpha-MSH related peptides: a new class of anti-inflammatory and immunomodulating drugs. Ann Rheum Dis. 2007 Nov;66 Suppl 3(Suppl 3):iii52-5.

(6) Kannengiesser K, Maaser C, Heidemann J, Luegering A, Ross M, Brzoska T, Bohm M, Luger TA, Domschke W, Kucharzik T. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease. Inflamm Bowel Dis. 2008 Mar;14(3):324-31.

Peptide Storage & Reconstitution

The Peptide Vial holds a white, lyophilised solid peptide that dissolves easily in clinical-grade sterile or bacteriostatic water.

To preserve the quality and stability of peptides, store them in a cool, dry place, away from heat and direct sunlight.

Refrigeration is highly recommended, with optimal storage temperatures between 2°C and 8°C.

Keeping peptides in tightly sealed vials or containers prevents exposure to air and moisture, which can compromise their quality.

Following these storage guidelines helps extend the shelf life of peptides, ensuring their reliability for research and therapeutic use.

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DISCLAIMER:

All products sold by Revitalife are for research and laboratory use only.

These products are not designed for use or consumption by humans or animals.

They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

By purchasing from our Website the buyer accepts and acknowledges the risks involved with handling of these products.

All articles and product information provided on this Website are for informational and educational purposes only. Handling and use of these products should be restricted to suitably qualified professional